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September 1, 1996Journal of Biological ChemistryOpen Access

Degradation of a Mutant Secretory Protein, α1-Antitrypsin Z, in the Endoplasmic Reticulum Requires Proteasome Activity

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Authors

DQDongfeng QuUniversity of Oklahoma Health Sciences CenterJTJeffrey TeckmanApple (Israel)SŌSatoshi ŌmuraWesleyan University

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Qu et al. (1996) studied this question.

synapsesocial.com/papers/6a6cf03d75498292b707ae6fhttps://doi.org/10.1074/jbc.271.37.22791
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Also Consider

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  1. 1Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin1995 · 1,599 citations
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  3. 3Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.1994 · 847 citations
  4. 4Conformational Changes Induced in the Endoplasmic Reticulum Luminal Domain of Calnexin by Mg-ATP and Ca2+1995 · 130 citations
  5. 5A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency.1994 · 292 citations