Key result
Children with isolated secundum atrial septal defect had significantly prolonged mean P wave dispersion compared to healthy controls (29.1 vs 25.3 ms, p=0.009).
Why the study?
Ostium secundum defect is a common cause of right atrial enlargement, prompting evaluation of P wave dispersion in relation to atrial septal defect size in children.
Does the presence and size of secundum atrial septal defect increase P wave dispersion and P maximum in pediatric patients?
Case-Control (n=82)
No
Does the presence and size of secundum atrial septal defect increase P wave dispersion and P maximum in pediatric patients?
Absolute Event Rate: 29.1% vs 25.3%
p-value: p=0.009
P wave dispersion and P maximum are significantly prolonged in children with moderate to large ASD or right atrial dilation, offering a potential ECG-based diagnostic tool when echocardiography is unavailable.
May signal subclinical atrial vulnerability in pediatric ASD; leaves open whether P wave dispersion aids risk stratification or monitoring.
Objective:Ostium secundum defect is the common cause of RA enlargement. The aim in this study is to evaluate P wave dispersion in children to the size of atrial septal defect.Method:Forty–one children with isolated secundum atrial septal defect (and 41 age-matched controls evaluated. Using the same 12 lead ECG device in resting position, P maximum and P dispersion measured.Results:Mean P dispersion in atrial septal defect children is prolonged compare to the controls (P dispersion: 29.1±10.1 vs. 25.3±5.5 ms, P=0.009). And children with right atrial dilation had significantly longer P maximum (101.2±14.1 vs. 81.7±12.3 ms, P<0.001) and larger P dispersion (35.0±11.4 vs. 26.5±8.3 ms, P=0.003) compared to those without right atrial dilation.Conclusion:Children with moderate to large sized ASD are valuable to have prolonged. Atrial conduction time in the form of P duration and P dispersion. Also, it’s a good tool for diagnosing ASD in places where echocardiography imaging is not available. We can also differentiate between small ASD and large one based on P dispersion.
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Salih et al. (2019) conducted a case-control in Secundum atrial septal defect (n=82). Secundum atrial septal defect vs. Healthy age-matched controls was evaluated on P wave dispersion (p=0.009). Children with isolated secundum atrial septal defect had significantly prolonged mean P wave dispersion compared to healthy controls (29.1 vs 25.3 ms, p=0.009).
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