Key result
Captopril 25 mg 3 times/day improved the daily profile of plasma glucose levels and augmented postprandial forearm blood flow in 12 non-insulin-dependent diabetic normotensive subjects.
Why the study?
Does captopril improve plasma glucose concentration in non-insulin-dependent diabetic normotensive subjects?
Population
12 non-insulin-dependent diabetic normotensive subjects
Comparison
Captopril 25 mg 3 times/day vs Without captopril
Design
Other
Authors
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Hypothesis-generating for captopril's glycemic effects in type 2 diabetes; larger RCTs needed before any clinical consideration.
Does captopril improve plasma glucose concentration in non-insulin-dependent diabetic normotensive subjects?
Captopril may improve glucose metabolism in diabetic subjects, potentially by enhancing blood flow to skeletal muscle.
Kodama et al. (1990) studied Non-insulin-dependent diabetes mellitus (n=12). Captopril vs. Without captopril was evaluated on Daily profiles of plasma glucose levels. Captopril 25 mg 3 times/day improved the daily profile of plasma glucose levels and augmented postprandial forearm blood flow in 12 non-insulin-dependent diabetic normotensive subjects.
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