Key result
Wedge pressure correlated poorly with left atrial pressure in over half of patients, especially in mitral stenosis with markedly elevated left atrial pressure.
Why the study?
Does wedge pressure accurately correlate with left atrial pressure in subjects with congenital and acquired heart disease?
Population
12 subjects with congenital and acquired heart disease
Comparison
Measurement of wedge pressure vs Measurement of left atrial pressure
Design
Cross-sectional
Authors
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Caution advised when relying on wedge pressure to estimate left atrial pressure in mitral stenosis; leaves open its reliability across other cardiac conditions.
Does wedge pressure accurately correlate with left atrial pressure in subjects with congenital and acquired heart disease?
Wedge pressure may be an inaccurate surrogate for left atrial pressure, particularly in patients with mitral stenosis and elevated left atrial pressures.
Jerome P. Murphy (1958) studied this question. Wedge pressure correlated poorly with left atrial pressure in over half of patients, especially in mitral stenosis with markedly elevated left atrial pressure.
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