What question did this study set out to answer?

To assess whether the Drorbaugh-Fenn formula underestimates barometric tidal volume based on breath timing and expired nasal temperature, and to derive an accurate correction factor.

August 1, 1980Journal of Applied Physiology

Barometric measurement of tidal volume: effects of pattern and nasal temperature

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To assess whether the Drorbaugh-Fenn formula underestimates barometric tidal volume based on breath timing and expired nasal temperature, and to derive an accurate correction factor.
Simultaneously measured tidal volume in anesthetized rats using a barometric chamber and conventional pneumotachography.
Varied expired nasal temperature using a heated pneumotachograph and adjusted the ratio of inspiratory duration to total breath duration by changing inspired carbon dioxide concentrations.
Measured expired nasal temperature across multiple species, including rats, rabbits, cats, humans, and infant pigtail monkeys.
Confirmed that the standard formula underestimates tidal volume by up to 30%, with error increasing as the inspiratory duration ratio and nasal temperature increase.
Derived a correction factor requiring nasal temperature and inspiratory timing that reduced inter-experiment error to under 20% and intra-experiment error to approximately 5%.

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Implication

Experimental study demonstrates that breathing pattern and nasal temperature bias barometric tidal volume estimates in anesthetized rats, indicating the necessity of a retrospective correction factor.

Cite This Study

J. Jacky (1980) studied this question.

synapsesocial.com/papers/6a6d03c45d37378ac1db6da7 https://doi.org/10.1152/jappl.1980.49.2.319

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Barometric measurement of tidal volume: effects of pattern and nasal temperature

Key Points

Discussion

Implication

Cite This Study

Barometric measurement of tidal volume: effects of pattern and nasal temperature

Key Points

Discussion

Implication

Cite This Study

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