Clinical guidance demonstrates the necessity of high-dose influenza vaccines in adults aged 65 and older, highlighting reduced standard vaccine efficacy caused by immunosenescence.
statistical Analysis, D -Data interpretation, E -Manuscript Preparation, F -literature search, G -Funds collection Annual vaccination is the most effective protection against influenza and its serious complications. it is especially important for people at high risk of severe course of the disease and serious complications: individuals with specific chronic medical conditions, pregnant women, children aged 6-59 months, older people, and healthcare workers.Despite a progressive increase in seasonal vaccine coverage, influenza-related morbidity, mortality, and hospitalization rates remain high and have continued to increase in people aged 65 years and over.standard vaccines against influenza are less efficient in this group due to immunosenescence.consequently, more effective vaccines are needed to prevent influenza and its complications in older adults.
No takes yet. Share an insight, caveat, or question.
Nitsch‐Osuch et al. (2024) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: