Key result
Multiplex RT-PCR assays identified respiratory viruses in 23% of adults with community-acquired pneumonia, with lower leukocyte counts distinguishing viral from bacterial etiology (P=0.004).
Why the study?
Does adding PCR to conventional laboratory tests improve the detection of respiratory viruses in adults with community-acquired pneumonia?
Population
198 adult patients diagnosed with community-acquired pneumonia from January 2003 to March 2004 who had…
Comparison
Addition of PCR to routine conventional… vs Routine conventional laboratory tests alone.
Design
Cohort
Authors
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Viruses cause ~23% of adult CAP; leaves open whether routine PCR and antivirals should enter practice.
Observational (n=198)
Does adding PCR to conventional laboratory tests improve the detection of respiratory viruses in adults with community-acquired pneumonia?
Adding PCR to routine laboratory tests significantly increases the detection of respiratory viruses as a common etiology of community-acquired pneumonia in adults.
Marcos et al. (2006) conducted an observational in Community-acquired pneumonia (n=198). Multiplex RT-PCR assays vs. Conventional laboratory tests was evaluated on Detection of respiratory viruses. Multiplex RT-PCR assays identified respiratory viruses in 23% of adults with community-acquired pneumonia, with lower leukocyte counts distinguishing viral from bacterial etiology (P=0.004).
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