Key result
Monitoring hCMV-specific T-cell responses using assays like IFN-γ ELISPOT and ELISA may add crucial information for predicting the risk of viral infection after renal transplantation.
Why the study?
Does monitoring hCMV-specific T-cell responses predict the risk of viral infection in kidney transplant recipients?
Does monitoring hCMV-specific T-cell responses predict the risk of viral infection in kidney transplant recipients?
Monitoring hCMV-specific T-cell responses may improve risk stratification for CMV infection in kidney transplant recipients, but requires standardization and validation in large trials.
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May refine post-transplant hCMV risk stratification; hypothesis-generating until randomized outcome trials confirm benefit.
Lúcia et al. (2014) conducted a review in hCMV infection in kidney transplantation. Monitoring hCMV-specific T-cell responses was evaluated. Monitoring hCMV-specific T-cell responses using assays like IFN-γ ELISPOT and ELISA may add crucial information for predicting the risk of viral infection after renal transplantation.
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