Key result
Atrial fibrillation was associated with increased full width and duration of Ca2+ sparks and increased frequency of Ca2+ waves in atrial myocytes compared to normal sinus rhythm.
Authors
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Altered RyR Ca²⁺ spark properties in human AF myocytes may reflect functional protein changes; leaves open causal role and therapeutic implications.
Observational (n=43)
Liang et al. (2008) conducted an observational in Atrial Fibrillation (n=43). Atrial fibrillation vs. Normal sinus rhythm was evaluated on Spontaneous Ca2+ sparks and Ca2+ waves. Atrial fibrillation was associated with increased full width and duration of Ca2+ sparks and increased frequency of Ca2+ waves in atrial myocytes compared to normal sinus rhythm.
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