Defining the relationship: The effect of catalyst acidity has been systematically probed by using a modular oxazoline catalyst in a hetero-Diels–Alder reaction catalyzed by hydrogen bonding. Linear free energy relationships were observed between the catalyst acidity and both the reaction rate and enantioselectivity (see picture).
No takes yet. Share an insight, caveat, or question.
Jensen et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: