Key result
Fatty infiltration into the myocardium may affect cardiac function and is associated with rupture during acute myocardial infarction, sudden death, and potential malignant transformation.
Fatty infiltration in the heart may have more significant clinical implications than traditionally taught, including increased risk of rupture during myocardial infarction and sudden death.
Current teaching is that fatty infiltration into the myocardium (lipomatosis or cor adiposum) rarely affects cardiac function. This may not be entirely true. Rupture during acute myocardial infarction has certainly been shown to be more common in the fatty heart.1 Fat infiltrating in the region of the conduction system is responsible for causing sudden death.2 Furthermore, it is possible for lipomatous hypertrophy in the heart to even undergo malignant transformation.3 Since fat is a normal constituent of the heart, it remains undefined as to exactly how much, and in which locations, one considers fatty …
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Liron Pantanowitz (2001) conducted a review in Fatty infiltration into the myocardium. Fatty infiltration into the myocardium was evaluated. Fatty infiltration into the myocardium may affect cardiac function and is associated with rupture during acute myocardial infarction, sudden death, and potential malignant transformation.
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