Key result
Resistance to stretch at low pressures in human iliac arteries is almost entirely due to elastin fibers, while at high pressures it is almost entirely due to collagenous fibers.
The non-linear distensibility of arteries is driven by elastin fibers at low pressures and collagen fibers at physiological and high pressures.
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Nonlinear arterial distensibility may refine hemodynamic models; leaves open quantitative validation of elastin-collagen recruitment in vivo.
Roach et al. (1957) studied Human iliac arteries from autopsy. Differential digestion of collagen and elastin vs. Before digestion was evaluated on Elastic diagrams (tension vs. circumference). Resistance to stretch at low pressures in human iliac arteries is almost entirely due to elastin fibers, while at high pressures it is almost entirely due to collagenous fibers.
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