Key result
A 72-year-old man with posterior mitral leaflet hypoplasia developed severe symptomatic mitral regurgitation years later due to chordal rupture and flail of the anterior mitral leaflet.
Case Report (n=1)
Posterior mitral leaflet hypoplasia is a rare condition in adults that can remain asymptomatic until complications like chordal rupture occur.
PML hypoplasia may warrant conservative management in adults given good prognosis; leaves open optimal intervention thresholds for symptomatic or atypical cases.
A 72-year-old man presenting with progressive dyspnea was evaluated. Transthoracic and consequently transesophageal echocardiography verified severe mitral regurgitation (MR) caused by hypoplasia of the posterior mitral leaflet (PML) and flail of A2 scallop. A review of reported cases reveals that PML hypoplasia is an uncommon diagnosis among the adult population which can be tolerated relatively well and carries a good prognosis. Our patient had a unique course of the disease. Previously presenting with a bicuspid aortic valve and a nonsignificant MR in spite of the severely hypoplastic PML. Eventually, he became symptomatic years later as severe MR developed due to chordal rupture and flail of the anterior mitral leaflet.
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Emami et al. (2024) conducted a case report in Severe mitral regurgitation and hypoplasia of the posterior mitral leaflet (n=1). Posterior mitral leaflet hypoplasia was evaluated. A 72-year-old man with posterior mitral leaflet hypoplasia developed severe symptomatic mitral regurgitation years later due to chordal rupture and flail of the anterior mitral leaflet.
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