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July 1, 2026Immunity Inflammation and DiseaseOpen Access

TRPM2 Deficiency Attenuates Allergic Rhinitis‐Like Inflammation With Altered Ca 2+ ‐NFAT Signaling, Treg Responses, and sIgE Production

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ZHZhenke HuangJFJianping FanXSXinxin Shan

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Huang et al. (2026) studied this question.

synapsesocial.com/papers/6a6d384d5d37378ac1db7dc9https://doi.org/10.1002/iid3.70490
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1TRPM2: bridging calcium and ROS signaling pathways—implications for human diseases2023 · 45 citations
  2. 2Nomenclature of allergic diseases and hypersensitivity reactions: Adapted to modern needs: An EAACI position paper2023 · 289 citations
  3. 3Severe inflammation in C57/BL6 mice leads to prolonged cognitive impairment by initiating the IL-1β/TRPM2 pathway2024 · 10 citations
  4. 4Nasal Microbiota as a Potential Therapeutic Target for Allergic Rhinitis: An Emerging Perspective2025 · 4 citations
  5. 5Role of Group 2 innate lymphoid cells in intranasal sensitization-induced allergic rhinitis in mice2025 · 3 citations