Key result
Radiofrequency catheter ablation of the moderator band directly terminated sustained ventricular fibrillation into monomorphic ventricular tachycardia within 3.8 seconds of energy application.
Why the study?
Does radiofrequency catheter ablation of the moderator band terminate sustained ventricular fibrillation in a patient with drug-refractory VF post-STEMI?
Case Report (n=1)
No
Does radiofrequency catheter ablation of the moderator band terminate sustained ventricular fibrillation in a patient with drug-refractory VF post-STEMI?
This first-in-human report demonstrates that radiofrequency catheter ablation of the moderator band can terminate sustained ventricular fibrillation, suggesting the Purkinje system's active role in VF perpetuation.
Moderator band ablation may terminate refractory post-MI VF; hypothesis-generating for Purkinje triggers, requiring prospective validation.
After a ST-segment elevation inferior myocardial infarction, a patient developed multiple drug-refractory ventricular fibrillation (VF), triggered by a stereotypic premature ventricular complex. During an episode of sustained VF, catheter ablation of the moderator band terminated VF, with transition into monomorphic ventricular tachycardia. To the best of our knowledge, this is the first-in-human report of termination of VF during delivery of radiofrequency energy, which suggests that the focal area on moderator band of Purkinje system had an active role in the perpetuation of VF. (Level of Difficulty: Advanced.)
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Narichania et al. (2022) conducted a case report in Ventricular fibrillation storm (n=1). Radiofrequency catheter ablation was evaluated on Termination of ventricular fibrillation. Radiofrequency catheter ablation of the moderator band directly terminated sustained ventricular fibrillation into monomorphic ventricular tachycardia within 3.8 seconds of energy application.
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