February 1, 1988Journal of Applied Physiology
Induction of upper airway occlusion in sleeping individuals with subatmospheric nasal pressure
Authors
Discussion
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Implication
Randomized trial examines upper airway occlusion and nasal pressure in sleeping individuals, suggesting critical pressure influences airflow.
Key Points
- This research aims to explore how nasal pressure affects airflow and induces airway occlusion during sleep.
- Examined seven normal subjects during NREM sleep with varying nasal pressures using a nasal mask.
- Monitored maximal inspiratory airflow and determined Pcrit from linear regression analysis.
- Investigated the occurrence of upper airway occlusions based on changes in nasal pressure.
- Found upper airway Pcrit to be -13.3 +/- 3.2 cmH2O.
- Demonstrated that nasal pressure below Pcrit led to recurrent occlusive apneas in subjects.
- Documented a linear relationship between inspiratory airflow and nasal pressure in each subject.
Cite This Study
Schwartz et al. (1988) studied this question.