Key result
Female sex is linked to ~3.1-fold higher odds of rheumatic heart disease.
Why the study?
Rheumatic heart disease is a neglected tropical disease and remains a leading cause of cardiovascular-related deaths in Ethiopia, but its burden and determinants needed assessment.
Cross-Sectional (n=340)
No
Odds Ratio: 3.06 (95% CI 1.73–5.47)
p-value: p=0.001
Rheumatic heart disease remains the leading cardiovascular etiology among clinical patients in Ethiopia (27.9%), driven heavily by correctable socio-environmental disparities such as indoor biomass fuel use, poor dental hygiene, malnutrition, and overcrowding.
Alerts clinicians to high RHD burden in Ethiopia; leaves open causal roles of sex and malnutrition pending prospective studies.
Rheumatic heart disease (RHD) is a neglected tropical disease and remains one of the leading causes of cardiovascular-related deaths in Ethiopia. This study aims to assess the burden of RHD and identify its determinants in the country. A hospital-based cross-sectional study was employed from January 5 to April 15, 2023, among cardiac patients attending Jimma Medical Center. Socio-demographic data were collected using a structured interviewer-administered questionnaire and echocardiographic patterns were taken by senior cardiologists. Data were entered into Epidata Version 4.6 and exported to SPSS version 25.0 for analysis. Bivariable and multivariable logistic regressions were performed. A p value < 0.05 was considered statistically significant. Accordingly, the most frequent morbidities were RHD (n = 95, 27.9 %), hypertensive heart disease (n = 92, 27.1 %), ischemic heart disease (n = 54, 15.9 %), and dilated cardiomyopathies (n = 54, 15.9 %). Further, female sex [AOR = 3.06: 95 % CI 1.73-5.47], using wood (biomass fuel) for cooking [AOR = 1.94: 95 % CI 1.10-3.42], history of malnutrition with follow-up at a health facility [AOR = 3.90: 95 % CI 2.22-6.86], dental caries [AOR = 2.09: 95 % CI 1.12-3.87], and living in crowded households [AOR = 2.02: 95 % CI 1.15-3.52] were identified as the determinants of RHD. This finding suggests that focusing on female healthcare, reducing biomass fuel exposure, improving nutritional status, providing regular dental care, and improving living conditions could help reduce the impacts of the disease. Moreover, conducting further research regularly will also benefit the community at large.
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Berhanu et al. (2024) conducted a cross-sectional in Cardiovascular disease (specifically Rheumatic heart disease) (n=340). Female sex vs. Male sex was evaluated on Rheumatic heart disease diagnosis (AOR 3.06, 95% CI 1.73-5.47, p=0.001). Rheumatic heart disease was the most frequent morbidity (27.9%); female sex (AOR 3.06) and malnutrition history (AOR 3.90) were significantly associated with the condition.
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