Key result
Oncogenic viruses, which are associated with approximately 10.8% of human cancers, require the host RNA splicing machinery to exercise their oncogenic activities.
Design
Review
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Targeting host RNA splicing may offer antiviral strategies against oncogenic viruses; leaves open clinical translation and efficacy.
Highlights the critical role of host RNA splicing machinery in the oncogenic activities of human tumor viruses.
Ajiro et al. (2014) conducted a review in Virus-induced human cancers. Oncogenic viruses was evaluated. Oncogenic viruses, which are associated with approximately 10.8% of human cancers, require the host RNA splicing machinery to exercise their oncogenic activities.
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