Key result
This review summarizes the epidemiology, pathophysiology, clinical features, and various pharmacological and non-pharmacological management strategies for neurogenic orthostatic hypotension.
Why the study?
Neurogenic orthostatic hypotension involves impaired blood pressure regulation from autonomic dysfunction, with diverse causes and symptoms that can make diagnosis challenging.
This review summarizes the current state of the art and therapeutic strategies for managing neurogenic orthostatic hypotension.
Clinicians may reference this synthesis for nOH management options; leaves open the need for prospective trials to strengthen evidence.
Neurogenic orthostatic hypotension (nOH) is a subtype of orthostatic hypotension in which patients have impaired regulation of standing blood pressure due to autonomic dysfunction. Several primary and secondary causes of this disease exist. Patients may present with an array of symptoms making diagnosis difficult. This review article addresses the epidemiology, pathophysiology, causes, clinical features, and management of nOH. We highlight various pharmacological and non-pharmacological approaches to treatment, and review the recent guidelines and our approach to nOH.
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Kalra et al. (2020) conducted a review in Neurogenic orthostatic hypotension. This review summarizes the epidemiology, pathophysiology, clinical features, and various pharmacological and non-pharmacological management strategies for neurogenic orthostatic hypotension.
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