Contrast-enhanced Mammography for Breast Cancer Screening in Women at Increased Risk: Comparison of Prevalence and Incidence Screens

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Contrast-enhanced mammography maintains its cancer detection ability and demonstrates improved specificity and accuracy in subsequent incidence screens compared to initial prevalence screens for women at increased risk of breast cancer. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Cheng‐Han Lee; Tali Amir; Varadan Sevilimedu; Sarah Eskreis‐Winkler; Delia Keating; Donna D’Alessio; Maxine S. Jochelson; Gordon P. Watt; Kimberly Feigin; Noam Nissan; Hila Fruchtman-Brot; Christopher Comstock; Janice S. Sung

doi:10.1148/radiol.252433

July 1, 2026Radiology

Contrast-enhanced Mammography for Breast Cancer Screening in Women at Increased Risk: Comparison of Prevalence and Incidence Screens

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Abstract

The ability of contrast-enhanced mammography to help detect cancer during prevalence screening in women at increased risk for breast cancer is maintained in subsequent incidence screens, with better specificity and accuracy.

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Lee et al. (2026) studied this question.

synapsesocial.com/papers/6a6d7c3ca528af2d65c2a271 https://doi.org/10.1148/radiol.252433

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Contrast-enhanced Mammography for Breast Cancer Screening in Women at Increased Risk: Comparison of Prevalence and Incidence Screens

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Contrast-enhanced Mammography for Breast Cancer Screening in Women at Increased Risk: Comparison of Prevalence and Incidence Screens

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Abstract

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