Key result
A preprocedural monocyte to HDL cholesterol ratio >14 predicted stent restenosis with 71% sensitivity and 69% specificity in patients with angina pectoris undergoing bare-metal stenting.
Why the study?
Does the preprocedural monocyte to HDL ratio predict stent restenosis in patients with stable and unstable angina pectoris undergoing bare-metal stenting?
Cohort (n=831)
Does the preprocedural monocyte to HDL ratio predict stent restenosis in patients with stable and unstable angina pectoris undergoing bare-metal stenting?
An elevated preprocedural monocyte to HDL ratio (>14) may serve as an independent predictor of stent restenosis in patients receiving bare-metal stents.
Answers are grounded in this paper and cite their sources.
MHR may aid post-stent risk stratification in angina; hypothesis-generating and should not yet change practice.
AIM: This study aims to assess the predictive role of the preprocedural circulating monocyte to high-density lipoprotein (HDL) cholesterol ratio (MHR) on the occurrence of stent restenosis (SR) in patients with stable and unstable angina pectoris undergoing successful bare-metal stenting (BMS). PATIENTS & METHODS: Between February 2008 and June 2014, a total of 831 patients with stable and unstable angina pectoris who underwent successful BMS were retrospectively analyzed. Demographic and clinical characteristics of the patients were recorded. Left ventricular ejection fraction and laboratory data were also noted. RESULTS: In the receiver operating characteristics curve analysis, MHR >14 had 71% sensitivity and 69% specificity in predicting SR. CONCLUSION: Our study results show that preprocedural MHR is an independent predictor of SR in this patient population.
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Tok et al. (2016) conducted a cohort in Stable and unstable angina pectoris (n=831). Preprocedural monocyte to HDL cholesterol ratio (MHR) was evaluated on Stent restenosis. A preprocedural monocyte to HDL cholesterol ratio >14 predicted stent restenosis with 71% sensitivity and 69% specificity in patients with angina pectoris undergoing bare-metal stenting.
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