Key result
Amiodarone causes thyroid dysfunction in 15-20% of patients, requiring structured monitoring and phenotype-directed management to preserve arrhythmia control.
Why the study?
Amiodarone is an effective antiarrhythmic agent but causes thyroid dysfunction in 15-20% of patients, leading to amiodarone-induced hypothyroidism and thyrotoxicosis.
How should amiodarone-associated thyroid dysfunction be managed in clinical practice?
Design
Narrative review
Authors
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Reinforces tailored amiodarone thyroid management in practice; leaves open need for prospective trials to validate protocols.
How should amiodarone-associated thyroid dysfunction be managed in clinical practice?
This review provides a practical, guideline-based framework for managing amiodarone-induced thyroid dysfunction, emphasizing that arrhythmia control can often be preserved through phenotype-directed thyroid therapy.
Nagesh et al. (2026) conducted a review in Amiodarone-associated thyroid dysfunction. Amiodarone was evaluated. Amiodarone causes thyroid dysfunction in 15-20% of patients, requiring structured monitoring and phenotype-directed management to preserve arrhythmia control.
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