Key result
Hypotension induced with halothane and labetalol decreased mean arterial pressure by an average of 30% and heart rate by 8% in children undergoing operation for postductal coarctation of the aorta.
Why the study?
Does labetalol combined with halothane safely induce hypotension in children undergoing operation for postductal coarctation of the aorta?
Observational (n=9)
Does labetalol combined with halothane safely induce hypotension in children undergoing operation for postductal coarctation of the aorta?
Labetalol combined with halothane effectively and safely induces hypotension during surgery for postductal coarctation of the aorta in children.
May support labetalol-halothane for controlled hypotension in pediatric coarctation repair; leaves open confirmation in prospective trials.
Hypotension was induced with halothane and labetalol, an alpha and beta adrenergic blocking agent, in nine children undergoing operation for postductal coarctation of the aorta. The mean arterial pressure decreased by an average of 30% following labetalol, and in six patients the initial halothane concentration (1%) had to be reduced during this period. The heart rate decreased by an average of 8% after labetalol. Profound beta-blockade did not occur, and operating conditions were considered satisfactory. The usefulness of labetalol in the postoperative period is suggested.
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Susun E.F. Jones (1979) conducted an observational in Postductal coarctation of the aorta (n=9). Halothane and labetalol was evaluated on Mean arterial pressure and heart rate. Hypotension induced with halothane and labetalol decreased mean arterial pressure by an average of 30% and heart rate by 8% in children undergoing operation for postductal coarctation of the aorta.
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