Randomized trial evaluates pumpkin seed oil's effect on hormonal balance in men with gynecomastia, suggesting its safety and efficacy.
Key Points
This research aims to evaluate the effectiveness of pumpkin seed oil supplementation in men with early-stage gynecomastia by measuring hormone levels and clinical symptoms.
Participants aged 18-50 with early-stage gynecomastia received standardized pumpkin seed oil supplementation for several weeks.
Serum testosterone and estradiol levels were measured before and after intervention.
Clinical symptom severity was evaluated and safety assessed through self-reports.
Testosterone levels increased from 513 ± 35 to 539 ± 35 ng/dL (+5.07%).
Estradiol levels decreased from 30.8 ± 3.5 to 26.4 ± 3.0 pg/mL (-14.16%).
85% of participants reported no adverse effects, and clinical symptom severity score improved from 2.5-3.0 to approximately 1.2.