PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
August 1, 2026The Journal of Headache and PainOpen Access

Migraine-related differences in connectivity patterns during emotional audiovisual processing revealed by functional connectivity multivariate pattern analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

KKKeva KlamerJCJoshua CraigCHChristina Haines

Discussion

Loading...

Member takes

Overview

Randomized trial demonstrates altered network interactions during emotional processing in migraineurs, suggesting heightened sensitivity to emotional stimuli.

Key Points

  • This study aims to explore how migraine impacts large-scale network interactions during emotional audiovisual processing.
  • Collected fMRI data from 22 migraineurs and 21 healthy controls using three audiovisual films.
  • Applied functional connectivity multivariate pattern analysis (fc-MVPA) to identify connectivity patterns.
  • Compared network interactions during different emotional conditions: negative valence/high arousal, positive valence/high arousal, and neutral valence/low arousal.
  • During the negative valence/high arousal condition, migraineurs showed greater within-network connectivity in the superior lateral occipital cortex (DMN) compared to controls.
  • Increased cross-network coupling with the attention, control, and visual networks was observed in the migraine group.
  • Network connectivity differences were not evident during positive valence/high arousal or neutral valence/low arousal conditions.

Cite This Study

Klamer et al. (2026) studied this question.

synapsesocial.com/papers/6a6d984be258b358b3c6b6dfhttps://doi.org/10.1186/s10194-026-02470-4
View Full Paper
Ask AI
Bookmark
Share