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August 1, 2026Russian Journal of Archive of Pathology

Clinical and morphological study of the prognostic value of tumor deposits in colorectal cancer

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Authors

NKNatalia V. KretovaSechenov UniversityТДТ. А. ДемураSechenov UniversityАSА. Yu. SuvorovSechenov University

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Implication

Randomized trial studies disease-free survival in patients with colorectal cancer, indicating tumor deposits impact prognosis.

Key Points

  • To evaluate the clinical and morphological characteristics of tumor deposits in colorectal cancer and their effect on disease-free survival.
  • Retrospective analysis of medical histories of 60 colorectal cancer patients treated at Sechenov University, 29 with tumor deposits and 31 without.
  • Comparison of clinical features including gender, age, tumor stage (TNM), localization, malignancy degree, and invasions.
  • Disease-free survival monitored for 36 months, analyzing locoregional recurrences and distant metastases.
  • Patients with tumor deposits had a 4.4 times higher chance of recurrence than those without (p=0.031).
  • Average time to recurrence was significantly shorter in the tumor deposit group at 26.1±13.2 months compared to 32.8±8.4 months in the group without deposits (p=0.013).
  • Tumors with tumor deposits were more frequently located in the left half of the colon and rectum and showed higher rates of perineural invasion (p=0.016).

Cite This Study

Kretova et al. (2026) studied this question.

synapsesocial.com/papers/6a6d9868e258b358b3c6bbebhttps://doi.org/10.17116/patol20268804114
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