Key result
Transcatheter aortic valve replacement was associated with similar in-hospital mortality to surgical replacement (2.3% vs 2.4%; P=0.71) but lower incidence of myocardial infarction and stroke.
Why the study?
Does TAVR reduce in-hospital mortality and complications compared to SAVR in patients with prior CABG requiring aortic valve replacement?
Cohort (n=15,055)
Yes
Does TAVR reduce in-hospital mortality and complications compared to SAVR in patients with prior CABG requiring aortic valve replacement?
Absolute Event Rate: 2.3% vs 2.4%
p-value: p=0.71
In patients with prior CABG requiring aortic valve replacement, TAVR is associated with similar in-hospital mortality but significantly lower rates of perioperative complications like MI, stroke, and bleeding compared to SAVR.
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TAVR utilization rose with similar mortality to SAVR in prior CABG; leaves open whether randomized trials will confirm lower complications.
Gupta et al. (2018) conducted a cohort in Aortic valve disease with prior coronary artery bypass grafting (n=15,055). Transcatheter aortic valve replacement (TAVR) vs. Surgical aortic valve replacement (SAVR) was evaluated on In-hospital mortality (p=0.71). Transcatheter aortic valve replacement was associated with similar in-hospital mortality to surgical replacement (2.3% vs 2.4%; P=0.71) but lower incidence of myocardial infarction and stroke.
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