Key result
The ERAS protocol significantly reduced median length of stay compared to standard care (9 vs. 12 days, p=0.024), with no significant difference in postoperative complications (42.8% vs. 37%, p=0.48).
Why the study?
The study aimed to compare intra- and postoperative outcomes between the Enhanced Recovery After Surgery protocol and the standard of care protocol in patients undergoing radical cystectomy performed by a single surgeon.
Does the ERAS protocol improve postoperative outcomes in patients undergoing radical cystectomy compared to standard of care?
Cohort (n=91)
Yes
Does the ERAS protocol improve postoperative outcomes in patients undergoing radical cystectomy compared to standard of care?
Absolute Event Rate: 42.8% vs 37%
p-value: p=0.48
Even partial adherence to the ERAS protocol in radical cystectomy can significantly reduce length of stay without increasing complications compared to standard care.
Background and Objectives: The aim was to compare the intra and postoperative outcomes between the Enhanced Recovery After Surgery (ERAS) protocol versus the standard of care protocol (SCP) in patients who underwent radical cystectomy performed by a single surgeon. Materials and Methods: A retrospective comparative study was conducted including patients who underwent radical cystectomy from 2017 to 2020. Length of stay (LOS), incidence of ileus, early postoperative complications, and number of re-hospitalizations within 30 days were considered as primary comparative outcomes of the study. Results: Data were collected for 91 patients who underwent cystectomy, and 70 and 21 patients followed the SCP and ERAS protocol, respectively. The mean age of the patients was 70.6 (SD 9.5) years. Although there was a statistically significant difference in time to flatus (TTF) [3 (2.7−3) vs. 1 (1−2 IQR) days, p < 0.001, in the SC hospital and in the ERAS center respectively], no difference was reported in time to first defecation (TTD) [5 (4−6) vs. 4 (3−5.8), p = 0.086 respectively]. The median LOS in the SCP group was 12 (IQR 11−13) days vs. 9 (IQR 8−13 p = 0.024). In the postoperative period, patients reported 22 complications (37% in SCP and 42.8% in ERAS group, p = 0.48). Conclusions: The study reveals how even partial adherence to the ERAS protocols leads to similar outcomes when compared to SCP. As a single surgeon series, our study confirmed the role of surgeons in reducing complications and improving surgical outcomes.
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Tulone et al. (2022) conducted a cohort in radical cystectomy (n=91). Enhanced Recovery After Surgery (ERAS) protocol vs. Standard of care protocol (SCP) was evaluated on Early postoperative complications (p=0.48). The ERAS protocol significantly reduced median length of stay compared to standard care (9 vs. 12 days, p=0.024), with no significant difference in postoperative complications (42.8% vs. 37%, p=0.48).
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