Novel chiral stationary phases improved enantioseparation in high-performance liquid chromatography, suggesting enhanced selectivity.
Two novel chiral stationary phases with different spacers were prepared by bonding a chiral trianglsalen macrocycle to thiol-functionalized silica via a thiol-ene click reaction for HPLC enantioseparation, exhibiting excellent enantioselectivity.
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Wu et al. (2025) studied this question.
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