Key result
A higher number of administered drug classes was associated with a lower risk of the composite of hospitalisation or death (p=0.001) among heart failure patients in the Philippines.
Why the study?
Data on follow-up outpatient care after discharge were sparse among past heart failure registries in the Philippines.
Observational (n=394)
Yes
p-value: p=0.001
A Philippine heart failure registry reveals suboptimal use of guideline-directed medical therapy, which correlates with high rates of hospitalization and mortality.
Supports electronic HF registry feasibility in the Philippines; leaves open questions on scalability and outcome impact.
Background: There have been several past registries of heart failure (HF) in the Philippines, but data on follow-up outpatient care after discharge were sparse. This study aimed to describe the characteristics, treatment patterns and outcomes of HF patients enrolled in a purely electronic HF registry. Methods: This HF registry is a pilot, non-interventional, longitudinal, multicentre registry of adult HF patients enrolled from three study sites. The HF registry used an electronic medical record application for data collection. Results: The three study sites enrolled 394 HF patients. The majority were male (72.34%) and the mean age was 56.91 ± 14.15 years. Only 75 patients (18.84%) had natriuretic peptide measurement. Regarding HF type, the majority had HF with reduced ejection fraction (EF) (41.12%) or HF with preserved EF (24.11%) while 22.59% had HF with mildly reduced EF; however, 12.18% were unclassified due to lack of echocardiography results. Overall, only 12.18% received four drug classes and 24.27% received three drug classes. Most patients (84.77%) had at least one follow-up visit. During follow-up, 6.60% of patients experienced acute decompensation and 20.81% were hospitalised. The mortality rate was 15.48%. The number of drug classes administered was associated with a lower risk of decompensation (p=0.030) or the composite of hospitalisation or death (p=0.001). Conclusion: This pilot HF registry showed that a purely electronic HF registry is implementable across various types of healthcare institutions. The majority of HF patients in the Philippines receive only suboptimal pharmacotherapy, which may contribute to high 12-month hospitalisation and mortality rates.
No takes yet. Share an insight, caveat, or question.
Reyes et al. (2025) conducted an observational in Heart failure (n=394). Number of drug classes administered was evaluated on Composite of hospitalisation or death (p=0.001). A higher number of administered drug classes was associated with a lower risk of the composite of hospitalisation or death (p=0.001) among heart failure patients in the Philippines.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: