Key result
Velocity vector imaging of the apical four-chamber view showed significant positive correlations (r=0.53 to 0.89) with the short-axis view for left ventricular myocardial motion parameters in rats.
Why the study?
To evaluate the correlation between apical four-chamber view and short-axis myocardial movement in rats using velocity vector imaging technology.
Effect estimate: r = 0.53 to 0.89
p-value: p=<0.05
Velocity vector imaging (VVI) is a feasible and valuable tool for evaluating left ventricular myocardial motion in the apical four-chamber view of rat models.
AIM: To use velocity vector imaging (VVI) technology to evaluate the correlation between the apical four-chamber view and short-axis myocardial movement in rats. METHODS: We used 25 10-week-old male Sprague-Dawley rats to measure the myocardium peak systolic velocity (Vs; cm/s), peak diastolic velocity (Vd; cm/s), peak systolic strain (SR; %), peak systolic strain rate (SRs; 1/s), and peak diastolic strain rate (SRd; 1/s) from the apical four-chamber view of the left ventricle (LV) and the parasternal mitral valve (PMV)-level short-axis view, and to analyze the correlation between myocardial motion in corresponding views of the two sections. RESULTS: Comparing the myocardial motion between the lateral wall's basal segment in the apical four-chamber view of the LV and the lateral wall of the PMV-level short-axis view revealed that the Vd was positively correlated (r = 0.59, p<0.01), as was SRs (r = 0.68, p<0.05). Comparing the myocardial motion between the lateral wall's middle segment in the apical four-chamber view of the LV and the lateral wall of the PMV-level short-axis view demonstrated that Vd, SRs, and SRd were positively correlated (r = 0.63, 0.82, 0.79, respectively, all p<0.01). Our comparison of myocardial motion between the posterior septum's basal segment in the apical four-chamber view of the LV and the posterior septum of PMV-level short-axis view showed that Vd and SRs were positively correlated (r = 0.57, 0.68, respectively, both p<0.01). Comparing the myocardial motion between the posterior septum's middle segment in the apical four-chamber view of the LV and the posterior septum of the PMV-level short-axis view revealed that Vs, Vd, SR, and SRd were positively correlated (r = 0.89, 0.63, 0.64, 0.6, respectively, all p<0.01), and the SRs also had a significant positive correlation (r = 0.53, p<0.05). CONCLUSION: VVI technology could be a valuable tool for evaluating the myocardial walls motion of the apical four-chamber view of the rat LV.
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Jin et al. (2020) studied Healthy (n=25). Velocity vector imaging (apical four-chamber view) vs. Parasternal mitral valve-level short-axis view was evaluated on Correlation of myocardial motion parameters between apical four-chamber and short-axis views (r = 0.53 to 0.89, p=<0.05). Velocity vector imaging of the apical four-chamber view showed significant positive correlations (r=0.53 to 0.89) with the short-axis view for left ventricular myocardial motion parameters in rats.
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