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May 1, 1985Proceedings of the National Academy of SciencesOpen Access

Rapid processing of the carboxyl terminus of a trypanosome variant surface glycoprotein.

James D. Bangs Dale Hereld Jessica Krakow Gerald W. Hart Paul T. Englund

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Abstract

The variant surface glycoprotein of the parasite Trypanosoma brucei contains a glycolipid of unknown structure covalently attached to its COOH terminus. We have shown, by using metabolic labeling with [35S]methionine or [3H]myristic acid, precipitation with specific antibodies, and NaDodSO4/polyacrylamide gel electrophoresis, that this glycolipid is attached to the variant surface glycoprotein polypeptide within 1 min after its translation.

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Cite This Study

Bangs et al. (1985) studied this question.

synapsesocial.com/papers/6a6de1bbf44fa9f079dbe242 https://doi.org/10.1073/pnas.82.10.3207

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