shown higher anxiety scores among patients with no previous or unpleasant previous anaesthetic experience compared with those whose previous experience had been pleasant.This was also the case in this study, and the table shows the anxiety shown by these more nervous patients (n=50).These patients had a lower anxiety score after they took timolol 10 mg.This effect was often described as "a surprising absence of the 'butterflies'."Scores changed little after placebo.The change in mean anxiety score was compared for the timolol and placebo groups by the paired two sample t test, and the reduction in the multiple affect adjective checklist score was significant (t= 2 05, 48 df; p<005).
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Karim Meeran (1989) studied this question.
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