Endoscopic CO2 laser excisional biopsy of selected early supraglottic cancer patients has been described. None of these patients experienced the perioperative morbidities of bleeding, airway obstruction, or aspiration beyond 3 or 4 days. All patients were treated with full-course standard irradiation therapy after their laser procedures. Our very preliminary data suggest that stage I and stage II patients are effectively treated with endoscopic CO2 laser excisional biopsy, whereas stage III patients should undergo open surgeries where medically possible.
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Davis et al. (1991) studied this question.
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