Key result
Adiponectin, leptin, and FGF21 mediated the relationship between abdominal adiposity and insulin resistance in South Asian men, but not in Malay or Chinese men.
Cross-Sectional (n=264)
Adipocytokines such as adiponectin, leptin, and FGF21 mediate the relationship between abdominal adiposity and insulin resistance in South Asian men, but not in Chinese or Malay men, highlighting ethnic-specific metabolic pathways.
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Adipocytokine-obesity-insulin sensitivity links differ by Asian ethnicity; leaves open whether they mediate intergroup variation.
Rizi et al. (2015) conducted a cross-sectional in Insulin resistance and abdominal adiposity (n=264). Abdominal adiposity and adipocytokines vs. Differences between ethnic groups was evaluated on Insulin sensitivity index (ISI). Adiponectin, leptin, and FGF21 mediated the relationship between abdominal adiposity and insulin resistance in South Asian men, but not in Malay or Chinese men.
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