Key result
Among pregnant women with congenital heart disease, mean birth weight was not significantly different between those with corrected versus uncorrected lesions (2593 g vs 2294 g; P=0.22).
Observational (n=27)
No
Absolute Event Rate: 2593% vs 2294%
p-value: p=0.22
Pregnant women with congenital heart disease in low-resource settings face high rates of adverse maternal and perinatal outcomes, highlighting the need for earlier diagnosis and planned pregnancies.
OBJECTIVE: To assess maternal and perinatal outcomes among pregnant women with congenital heart disease (CHD) in a low-resource country. METHODS: A prospective, observational study was conducted at a teaching hospital in Kolkata, India, between January 1, 2008, and December 31, 2010. All pregnant women with CHD were followed up from first prenatal visit to discharge. Both maternal and perinatal outcomes were analyzed. RESULTS: Of 174 pregnant women with heart disease, 27 (16%) had CHD. Mean age was 23.5±3.6 years. Four (15%) patients were diagnosed with CHD during the index pregnancy. Nine (33%) women had undergone surgical correction before conception. Cesarean delivery was performed in 12 (44%) women. Fifteen (56%) neonates weighed less than 2500 g, and 4 (15%) were born preterm. Mean birth weight was slightly higher in women with corrected heart lesions than in those with uncorrected ones (2593±480 g vs 2294±620 g; P=0.22). Three (11%) neonates died, but no stillbirths occurred. One (4%) woman died after delivery owing to atonic postpartum hemorrhage. CONCLUSION: Delayed diagnosis, lack of treatment, and unplanned pregnancy are major challenges for women with CHD, which need to be addressed to improve maternal and neonatal outcomes in low-resource countries.
No takes yet. Share an insight, caveat, or question.
Arora et al. (2014) conducted an observational in Congenital heart disease in pregnancy (n=27). Corrected congenital heart lesions vs. Uncorrected congenital heart lesions was evaluated on Mean birth weight (p=0.22). Among pregnant women with congenital heart disease, mean birth weight was not significantly different between those with corrected versus uncorrected lesions (2593 g vs 2294 g; P=0.22).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: