Key result
Early initiation of supportive treatment, including PEEP and vasoactive drugs, resulted in complete clinical and radiological resolution of unilateral neurogenic pulmonary edema following aneurysm clipping.
Case Report (n=1)
Unilateral neurogenic pulmonary edema is a rare complication following clipping of a ruptured intracranial aneurysm that requires a high index of suspicion and responds well to early supportive therapy.
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Unilateral NPE may occur with aneurysmal vasospasm; extends the NPE spectrum but remains hypothesis-generating.
A variety of central nervous system lesions like stroke, subarachnoid haemorrhage, trauma and seizure activity can result in neurogenic pulmonary oedema (NPE). Unilateral neurogenic pulmonary oedema is very rare. There are no reports of unilateral NPE with aneurysmal vasospasm. We present the case of a 55-year-old female who developed respiratory distress with unilateral pulmonary oedema and mild left ventricular dysfunction in the context of postoperative cerebral vasospasm following clipping of ruptured intracranial aneurysm. Neurogenic pulmonary oedema should always be in the differential diagnosis when patients with presumed neurogenic pathology develop respiratory compromise. The diagnosis of unilateral neurogenic pulmonary oedema requires a high index of suspicion. Early initiation of supportive treatment results in good outcome.
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Durga et al. (2012) conducted a case report in Unilateral neurogenic pulmonary edema following clipping of ruptured intracranial aneurysm (n=1). Supportive treatment (diuretics, dobutamine, ACE inhibitors, PEEP) was evaluated on Resolution of pulmonary edema. Early initiation of supportive treatment, including PEEP and vasoactive drugs, resulted in complete clinical and radiological resolution of unilateral neurogenic pulmonary edema following aneurysm clipping.
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