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January 1, 1988Neurologia medico-chirurgicaOpen Access

Early Surgery for Ruptured Intracranial Aneurysms associated with Neurogenic Pulmonary Edema

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Key result

Early clipping plus PEEP successfully treats two patients with ruptured intracranial aneurysms and neurogenic pulmonary edema.

  • n=2

Why the study?

Does very early surgery combined with aggressive management of pulmonary edema improve outcomes in patients with ruptured intracranial aneurysms associated with neurogenic pulmonary edema?

Population

2 female patients with ruptured intracranial aneurysm associated with neurogenic pulmonary edema, both Hunt…

Design

Case_series

Follow-up

Until discharge

Authors

TKTakeshi KondohShinko HospitalKKKeiichi KuwamuraThe University of KitakyushuMMMasaru MiyataIshikawa Prefectural Central Hospital

Discussion

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Implication

May support ultra-early clipping plus PEEP in select aneurysmal SAH with NPE; hypothesis-generating and should not yet change practice.

Study Design

Type

Case Report (n=2)

Structured PICO

Does very early surgery combined with aggressive management of pulmonary edema improve outcomes in patients with ruptured intracranial aneurysms associated with neurogenic pulmonary edema?

P
Population
Two female patients, aged 53 and 55, with ruptured intracranial aneurysms and neurogenic pulmonary edema (Hunt and Kosnik grade 4) who underwent early surgical clipping.
I
Intervention
Very early surgery (aneurysm clipping at 3 and 4 hours) combined with intra- and postoperative respiratory maintenance with positive end-expiratory pressure.
O
Outcome
Neurological status at dischargehard clinical

Very early surgery combined with aggressive respiratory management using positive end-expiratory pressure can be successful in patients with ruptured intracranial aneurysms complicated by neurogenic pulmonary edema.

Limitations

  • Case report with only two patients
  • Optimal timing of surgery for ruptured cerebral aneurysms associated with neurogenic pulmonary edema has not been clearly determined

Cite This Study

Kondoh et al. (1988) conducted a case report in Ruptured intracranial aneurysm associated with neurogenic pulmonary edema (n=2). Early surgery (clipping) with positive end-expiratory pressure (PEEP) was evaluated on Clinical outcome at discharge. Early surgical clipping combined with positive end-expiratory pressure successfully treated two patients with ruptured intracranial aneurysms and neurogenic pulmonary edema, resulting in discharge without major neurological deficits.

synapsesocial.com/papers/6aa2998da25963cecb13a668https://doi.org/10.2176/nmc.28.1107
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Neurogenic Pulmonary Edema Associated with Ruptured Intracranial Aneurysm: Case Report1986 · 36 citations
  2. 2Pathogenesis of Neurogenic Pulmonary Edema1978 · 113 citations
  3. 3NEUROGENIC PULMONARY EDEMA1971 · 40 citations
  4. 4Delayed nonfatal pulmonary edema following subarachnoid hemorrhage1979 · 24 citations