Key result
In patients with NSTEMI undergoing percutaneous coronary intervention, diabetic patients had a significantly lower ejection fraction after 3 months compared to non-diabetic patients (57.12% vs 59.74%, p=0.005).
Why the study?
NSTEMI is a primary cause of global morbidity and mortality, but comparison of LV systolic function via 2D and speckle tracking echocardiography between diabetics and non-diabetics undergoing PCI remained to be evaluated.
Does diabetes mellitus impair the recovery of left ventricular systolic function in patients undergoing percutaneous coronary intervention for NSTEMI?
Cohort (n=100)
No
Does diabetes mellitus impair the recovery of left ventricular systolic function in patients undergoing percutaneous coronary intervention for NSTEMI?
Absolute Event Rate: 57.12% vs 59.74%
p-value: p=0.005
Diabetic patients with NSTEMI undergoing PCI have significantly less improvement in left ventricular ejection fraction and global longitudinal strain at 3 months compared to non-diabetic patients.
Speckle tracking findings on LV function by diabetes status post-PCI for NSTEMI are hypothesis-generating; larger trials needed before clinical adoption.
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Talha et al. (2023) conducted a cohort in Non-ST-elevated myocardial infarction (NSTEMI) (n=100). Diabetes mellitus vs. Non-diabetic patients was evaluated on Ejection fraction (EF) after 3 months (p=0.005). In patients with NSTEMI undergoing percutaneous coronary intervention, diabetic patients had a significantly lower ejection fraction after 3 months compared to non-diabetic patients (57.12% vs 59.74%, p=0.005).
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