Key result
High-sensitivity C-reactive protein (AUC 0.950) and T-wave inversion on stress ECG (AUC 0.940) were identified as strong noninvasive predictors of the coronary slow flow phenomenon.
Why the study?
Patients with coronary slow flow phenomenon frequently undergo repeated invasive and non-invasive testing, prompting the need to identify non-invasive predictors in patients presenting with chronic coronary syndrome.
Do non-invasive markers predict coronary slow flow phenomenon in patients with chronic coronary syndrome?
Case-Control (n=100)
No
Do non-invasive markers predict coronary slow flow phenomenon in patients with chronic coronary syndrome?
Effect estimate: AUC 0.950 (95% CI 0.887-0.984)
Absolute Event Rate: 7.5% vs 3.02%
p-value: p=<0.001
Non-invasive markers such as T-wave inversion, HsCRP, P-wave dispersion, and hematocrit can help predict the presence of coronary slow flow phenomenon in patients with chronic coronary syndrome.
May aid non-invasive CSFP identification in chronic coronary syndrome; leaves open prospective validation before clinical adoption.
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Lutf et al. (2023) conducted a case-control in Coronary slow flow phenomenon (n=100). Coronary slow flow phenomenon vs. Normal coronary angiography was evaluated on High sensitivity C-reactive protein (HsCRP) level as a predictor of CSFP (AUC 0.950, 95% CI 0.887-0.984, p=<0.001). High-sensitivity C-reactive protein (AUC 0.950) and T-wave inversion on stress ECG (AUC 0.940) were identified as strong noninvasive predictors of the coronary slow flow phenomenon.
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