Key result
A simplex-based design optimization algorithm automatically adjusted the reference Urolume geometry to reduce foreshortening by 20% while maintaining radial stiffness.
Effect estimate: 20% reduction
A finite element-based modeling strategy successfully optimized braided stent design by reducing foreshortening without compromising radial stiffness.
Computational models may aid braided stent optimization; leaves open clinical translation for improved deployment accuracy.
At present, the deployment of self-expandable braided stents has become a common and widely used minimally invasive treatment for stenotic lesions in the cardiovascular, gastrointestinal and respiratory system. To improve these revascularization procedures (e.g. increase the positioning accuracy) the optimal strategy lies in the further development of the stent design. In the context of optimizing braided stent designs, computational models can provide an excellent research tool complementary to analytical models. In this study, a finite element based modelling strategy is proposed to investigate and optimize the mechanics of braided stents. First a geometrical and finite element model of a braided Urolume endoprosthesis was built with the open source pyFormex design tool. The results of the reference simulation of the Urolume stent are in close agreement with both analytical and experimental data. Subsequently, a simplex-based design optimization algorithm automatically adjusts the reference Urolume geometry to facilitate precise positioning by reducing the foreshortening with 20% while maintaining the radial stiffness. Therefore, the proposed modelling strategy appears to be a promising optimization methodology in braided stent design.
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Beule et al. (2008) studied Stenotic lesions. Simplex-based design optimization algorithm vs. Reference Urolume geometry was evaluated on Foreshortening and radial stiffness (20% reduction). A simplex-based design optimization algorithm automatically adjusted the reference Urolume geometry to reduce foreshortening by 20% while maintaining radial stiffness.
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