Clinical trial of carbazepine (tegretol) in trigeminal neuralgia.

Carbazepine, Tegretol (5-carbamyl-dibenz (b,f)- azepin), originally known as G.32883 and introduced in 1959 as an anticonvulsant, was first shown to have some effect in relieving the pain oftrigeminal neural- gia by Blom (1962Blom ( , 1963)).Since then Spillane (1963Spillane ( , 1964)), McArdle (1963), and Taylor (1963) have confirmed that this drug has a specific effect in relieving the pain of trigeminal neuralgia in some 60 to 80 % of patients.