Key result
VVMnPO lesions in rats selectively reduced angiotensin-dependent salt appetite but enhanced salt appetite to deoxycorticosterone acetate, without affecting water intake.
Authors
Loading...
Suggests stimulus-specific VVMnPO control of salt appetite in rats; leaves open translation to human sodium homeostasis disorders.
Fitts et al. (1990) studied Salt appetite. Lesions of the ventral part of the ventral median preoptic nucleus (VVMnPO) was evaluated on Salt appetite after treatments with chronic oral captopril, sodium depletion, or deoxycorticosterone acetate. VVMnPO lesions in rats selectively reduced angiotensin-dependent salt appetite but enhanced salt appetite to deoxycorticosterone acetate, without affecting water intake.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: