High-valent sulfur fluorides as reactivity switches for PFAS-free benzene–azepine skeletal editing

motifs are PFAS-free fluorine architectures that retain the beneficial physicochemical properties of perfluoroalkyl groups while avoiding environmental persistence. This work establishes a sustainable and general strategy for fluorinated skeletal editing, offering a foundation for future design of PFAS-free agrochemical, medicinal, and material scaffolds.