Key result
Higher visceral adipose tissue area was significantly associated with an increased risk of incident metabolic syndrome, with an adjusted HR of 3.73 for the highest versus lowest quintile.
Why the study?
Does visceral and subcutaneous adipose tissue area affect the incidence of metabolic syndrome in an apparently healthy Asian population?
Population
1,964 apparently healthy Asian subjects who received health screenings
Comparison
Visceral adipose tissue and subcutaneous adipose… vs Lower VAT/SAT area
Design
Cohort
Follow-up
median 4.5 years
Authors
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VAT area may aid MS risk stratification in Asians; hypothesis-generating without causal evidence from observational data.
Cohort (n=1,964)
No
Does visceral and subcutaneous adipose tissue area affect the incidence of metabolic syndrome in an apparently healthy Asian population?
Hazard Ratio: 3.73 (95% CI 2.22–6.28)
p-value: p=<0.001
Visceral adipose tissue is significantly associated with an increased risk of incident metabolic syndrome, whereas subcutaneous adipose tissue may have a protective effect against individual components.
Kwon et al. (2017) conducted a cohort in Metabolic Syndrome (n=1,964). Visceral adipose tissue (VAT) area vs. Lowest quintile of VAT area was evaluated on Incident metabolic syndrome (HR 3.73, 95% CI 2.22-6.28, p=<0.001). Higher visceral adipose tissue area was significantly associated with an increased risk of incident metabolic syndrome, with an adjusted HR of 3.73 for the highest versus lowest quintile.
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