May 21, 2009Blood Coagulation & Fibrinolysis
5 flourouracil-induced apical ballooning syndrome: a case report
Key result
Fluorouracil chemotherapy was associated with the development of apical ballooning syndrome in a 79-year-old woman, which completely resolved after 4 weeks of medical therapy.
Population
79-year-old woman with metastatic colorectal cancer
Design
Case_report
Follow-up
4 weeks
Authors
Discussion
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Member takes
Implication
May warrant vigilance for Takotsubo during fluorouracil therapy; single case leaves association hypothesis-generating.
Study Design
Type
Case Report (n=1)
Structured PICO
P
Population
A 79-year-old woman who developed apical ballooning syndrome after chemotherapy with fluorouracil for metastatic colorectal cancer, followed for 4 weeks.
E
Exposure
Fluorouracil chemotherapy
O
Outcome
Development of apical ballooning syndrome (ABS)safety
This case report highlights that fluorouracil chemotherapy may be a potential trigger for apical ballooning syndrome (Takotsubo cardiomyopathy).
Cite This Study
Gianni et al. (2009) conducted a case report in Apical ballooning syndrome (n=1). Fluorouracil was evaluated on Development and resolution of apical ballooning syndrome. Fluorouracil chemotherapy was associated with the development of apical ballooning syndrome in a 79-year-old woman, which completely resolved after 4 weeks of medical therapy.