Nitrosoarenes as Versatile Precursors for ¹⁸ F-Fluorination

Q: What does this research mean for the field?

Nitrosoarenes can be used as versatile precursors for 18F-fluorination, providing a new route to access labeling precursors from aromatic amines. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Markus Laube; Silvia Roscales; Jens Pietzsch; Aurelio G. Csáky

doi:10.1021/acsomega.6c02349

May 26, 2026ACS OmegaOpen Access

Nitrosoarenes as Versatile Precursors for ¹⁸ F-Fluorination

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Key Points

The study aims to explore the potential of nitrosoarenes as precursors for fluorine-18 labeling.
Investigated the conversion of nitrosoarenes to fluorinated compounds.
Utilized various aromatic amines in the fluorination process.
Successfully labeled compounds using nitrosoarenes as versatile precursors.
Demonstrated efficient access to a range of fluorinated products.

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Implication

Research demonstrates the utility of nitrosoarenes for creating fluorine-18 labeled compounds, suggesting new pathways for radiopharmaceutical development.

Abstract

F labeling and now allows versatile access to labeling precursors from aromatic amines.

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Cite This Study

Laube et al. (2026) studied this question.

synapsesocial.com/papers/6a6ec244febe604dd7080cb0 https://doi.org/10.1021/acsomega.6c02349

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Nitrosoarenes as Versatile Precursors for ¹⁸ F-Fluorination

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Nitrosoarenes as Versatile Precursors for ¹⁸ F-Fluorination

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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