Key result
Densities of M2 receptor and IK,ACh were significantly higher in the left and right atrial appendages and left atrium compared to the right atrium, pulmonary vein, and superior vena cava (21.34 vs 8.24 pA/pF, p<0.05).
Authors
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Hypothesis-generating for regional atrial targeting; leaves open clinical relevance pending validation.
Absolute Event Rate: 21.34% vs 8.24%
p-value: p=<0.05
Huang et al. (2006) studied Atrial fibrillation (n=10). Amiodarone and vagal stimulation vs. Different tissue sites / baseline was evaluated on Densities of M2 receptor and IK,ACh (p=<0.05). Densities of M2 receptor and IK,ACh were significantly higher in the left and right atrial appendages and left atrium compared to the right atrium, pulmonary vein, and superior vena cava (21.34 vs 8.24 pA/pF, p<0.05).
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