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This study aims to investigate the association between occupational exposures and the incidence of chronic obstructive pulmonary disease (COPD).

April 17, 2011ThoraxOpen Access

Occupational exposures and chronic obstructive pulmonary disease: a hospital based case-control study

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This study aims to investigate the association between occupational exposures and the incidence of chronic obstructive pulmonary disease (COPD).
Case-control design with 110 COPD cases and 102 matched controls from respiratory clinics
Lifetime occupational exposure histories obtained through interviews and ALOHA Job Exposure Matrix
Logistic regression used to calculate odds ratios, adjusting for smoking and tuberculosis history
Adjusted ORs for COPD from JEM-derived high cumulative exposures: biological dust 2.1 (95% CI 1.1-4.2), mineral dust 1.1 (95% CI 0.6-2.4), gas and fumes 1.8 (95% CI 0.8-3.9)
Self-reported exposures showed higher risks: high dust exposure-years OR 5.9 (95% CI 2.6-13.2), high chemical and gas fumes exposure-years OR 3.6 (95% CI 1.6-7.9)
For ever smokers, the OR for COPD ranged from 5.0 to 5.5, and tuberculosis showed an OR of 7.7 to 8.1

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Case-control study investigates links between occupational exposures and COPD in a high tuberculosis population, indicating significant risks.

Govender et al. (2011) studied this question.

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Case-control study investigates links between occupational exposures and COPD in a high tuberculosis population, indicating significant risks.