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Research to define the pathogenesis of psoriasis, a common inflammatory skin disorder, has considerably increased the general understanding of T-cell–mediated autoimmune disorders. Psoriasis is increasingly a prime target for new pathogenesis-oriented biologic therapies. The authors of this article review genetic, clinical, and pathogenic aspects of psoriasis and discuss their implications for new therapies.
Schön et al. (Wed,) studied this question.